PD-L1 Analyte ControlDR
PD-L1 Analyte ControlDR consists of four different cell lines with PD-L1 expression levels of negative, low, medium, and high. Ideal for use as a same slide control for PD-L1 to demonstrate the sensitivity of the assay and improve confidence in the result.
PD-L1, also known as CD274 and B7 homolog 1 (B7-H1), is a checkpoint regulator in immune cells, it is expressed on immune or non-hematopoietic cells. Expression of the protein is seen during pregnancy where it has a role in supressing the immune system. PD-L1 induces an inhibitory signal in activated T-cells and promotes T-cell apoptosis. It is overexpressed in a number of different cancers where it is believed to play a significant role in the cancer’s ability to evade the immune system.